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Ticker
Trade Date
Filing Date
Name
Title
Code
Security
Amount
Price
Value
Trans.
Director
10% Owner
Mcap/AUM
2025-05-29
2025-05-30
AGARWAL SHEFALI
A - Grant
Stock Option (Right to Buy)
55,000
$0.00
1
$138.71M
2025-05-29
2025-05-30
EPSTEIN ROBERT
A - Grant
Stock Option (Right to Buy)
55,000
$0.00
1
$138.71M
2025-05-29
2025-05-30
JOOSS KARIN
A - Grant
Stock Option (Right to Buy)
55,000
$0.00
1
$138.71M
2025-05-29
2025-05-30
LEE MICHAEL STEWART
A - Grant
Stock Option (Right to Buy)
55,000
$0.00
1
$138.71M
2025-05-29
2025-05-30
MENDLEIN JOHN
A - Grant
Stock Option (Right to Buy)
55,000
$0.00
1
$138.71M
2025-05-29
2025-05-30
ABERNETHY MATT
A - Grant
Stock Option (Right to Buy)
110K
$0.00
1
$138.71M
2025-05-29
2025-05-30
MOZAFFARIAN NEELUFAR
A - Grant
Stock Option (Right to Buy)
55,000
$0.00
1
$138.71M
2025-05-29
2025-05-30
RASTETTER WILLIAM
A - Grant
Stock Option (Right to Buy)
55,000
$0.00
1
$138.71M
2025-05-29
2025-05-30
REDMILE GROUP, LLC
A - Grant
Stock Option (Right to Buy)
55,000
$0.00
1
$138.71M
2025-05-29
2025-05-30
XU YUAN
A - Grant
Stock Option (Right to Buy)
55,000
$0.00
1
$138.71M
2025-03-06
2025-03-06
WOLCHKO SCOTT
President and CEO
S - Sale
-113K
$1.00
-113K
1
$138.71M
2025-01-16
2025-01-16
VALAMEHR BAHRAM
President and CEO
A - Grant
Stock Option (Right to Buy)
1.30M
$0.00
1
$138.71M
2025-01-15
2025-01-16
BRESSI JEROME CHARLES
Chief Regulatory and Quality O...
A - Grant
Stock Option (Right to Buy)
250K
$0.00
1
$138.71M
2025-01-15
2025-01-16
BRESSI JEROME CHARLES
Chief Regulatory and Quality O...
A - Grant
Common Stock
65,000
$0.00
1
$138.71M
2025-01-15
2025-01-16
TAHL CINDY
Chief Legal & Compliance Offic...
A - Grant
Stock Option (Right to Buy)
275K
$0.00
1
$138.71M
2025-01-15
2025-01-16
TAHL CINDY
Chief Legal & Compliance Offic...
A - Grant
Common Stock
70,000
$0.00
1
$138.71M
2025-01-15
2025-01-16
BRESSI JEROME CHARLES
Chief Regulatory and Quality O...
A - Grant
Stock Option (Right to Buy)
250K
$0.00
1
$138.71M
2025-01-15
2025-01-16
BRESSI JEROME CHARLES
Chief Regulatory and Quality O...
A - Grant
Common Stock
65,000
$0.00
1
$138.71M
2025-01-15
2025-01-16
TAHL CINDY
Chief Legal & Compliance Offic...
A - Grant
Stock Option (Right to Buy)
275K
$0.00
1
$138.71M
2025-01-15
2025-01-16
TAHL CINDY
Chief Legal & Compliance Offic...
A - Grant
Common Stock
70,000
$0.00
1
$138.71M
2025-01-10
2025-01-13
BRESSI JEROME CHARLES
Chief Regulatory and Quality O...
S - Sale
Common Stock
-5,980
$2.00
-11,960
1
$138.71M
2025-01-10
2025-01-13
TAHL CINDY
Chief Legal & Compliance Offic...
S - Sale
Common Stock
-5,654
$2.00
-11,308
1
$138.71M
2025-01-10
2025-01-13
VALAMEHR BAHRAM
President and CEO
S - Sale
Common Stock
-8,705
$2.00
-17,410
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
J - Other
Class A Convertible Preferred Stock
116K
$8.00
930K
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
J - Other
Cash-settled Swaps
-56,331
$2.00
-113K
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
J - Other
Class A Convertible Preferred Stock
-116K
$8.00
-930K
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
J - Other
Common Stock
1.08M
$2.00
2.17M
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
J - Other
Class A Convertible Preferred Stock
116K
$8.00
930K
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
J - Other
Cash-settled Swaps
-56,331
$2.00
-113K
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
J - Other
Class A Convertible Preferred Stock
-116K
$8.00
-930K
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
J - Other
Common Stock
1.08M
$2.00
2.17M
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
J - Other
Common Stock
-1.08M
$2.00
-2.17M
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
P - Purchase
Common Stock
398K
$2.00
796K
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
S - Sale
Common Stock
-342K
$2.00
-683K
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
J - Other
Common Stock
-1.08M
$2.00
-2.17M
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
P - Purchase
Common Stock
398K
$2.00
796K
1
$138.71M
2024-12-20
2024-12-26
REDMILE GROUP, LLC
S - Sale
Common Stock
-342K
$2.00
-683K
1
$138.71M
2024-12-12
2024-12-16
REDMILE GROUP, LLC
C - Conversion
Class A Convertible Preferred Stock
-6,022
1
$138.71M
2024-12-12
2024-12-16
REDMILE GROUP, LLC
C - Conversion
Common Stock
30,110
1
$138.71M
2024-12-12
2024-12-16
REDMILE GROUP, LLC
C - Conversion
Class A Convertible Preferred Stock
-6,022
1
$138.71M
2024-12-12
2024-12-16
REDMILE GROUP, LLC
C - Conversion
Common Stock
30,110
1
$138.71M
2024-08-06
2024-08-07
XU YUAN
S - Sale
Common Stock
-633
$4.00
-2,532
1
$138.71M
2024-07-29
2024-07-31
MOZAFFARIAN NEELUFAR
A - Grant
Stock Option (Right to Buy)
80,000
$0.00
1
$138.71M
2024-07-29
2024-07-31
TAHL CINDY
General Counsel and Secretary
A - Grant
Common Stock
200K
$0.00
1
$138.71M
2024-07-29
2024-07-31
VALAMEHR BAHRAM
Chief R&D Officer
A - Grant
Common Stock
200K
$0.00
1
$138.71M
2024-06-07
2024-06-11
MENDLEIN JOHN
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2024-06-07
2024-06-11
AGARWAL SHEFALI
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2024-06-07
2024-06-11
COUGHLIN TIMOTHY
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2024-06-07
2024-06-11
EPSTEIN ROBERT
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2024-06-07
2024-06-11
JOOSS KARIN
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2024-06-07
2024-06-11
LEE MICHAEL STEWART
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2024-06-07
2024-06-11
RASTETTER WILLIAM
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2024-06-07
2024-06-11
REDMILE GROUP, LLC
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2024-06-07
2024-06-11
XU YUAN
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2024-03-21
2024-03-25
REDMILE GROUP, LLC
A - Grant
Pre-Funded Warrants to Purchase Common Stock
3.64M
$5.00
18M
1
$138.71M
2024-03-04
2024-03-05
DULAC EDWARD III
Chief Financial Officer
S - Sale
Common Stock
-2,447
$8.00
-19,576
1
$138.71M
2024-02-01
2024-02-02
TAHL CINDY
General Counsel and Secretary
A - Grant
Stock Option (Right to Buy)
425K
$0.00
1
$138.71M
2024-02-01
2024-02-02
VALAMEHR BAHRAM
Chief R&D Officer
A - Grant
Stock Option (Right to Buy)
450K
$0.00
1
$138.71M
2024-02-01
2024-02-02
WOLCHKO SCOTT
President and CEO
A - Grant
Stock Option (Right to Buy)
500K
$0.00
1
$138.71M
2024-02-01
2024-02-02
DULAC EDWARD III
Chief Financial Officer
A - Grant
Stock Option (Right to Buy)
425K
$0.00
1
$138.71M
2024-01-29
2024-01-30
DULAC EDWARD III
Chief Financial Officer
S - Sale
Common Stock
-1,849
$5.00
-9,245
1
$138.71M
2024-01-09
2024-01-10
DULAC EDWARD III
Chief Financial Officer
S - Sale
Common Stock
-7,028
$4.00
-28,112
1
$138.71M
2024-01-09
2024-01-10
TAHL CINDY
General Counsel and Secretary
S - Sale
Common Stock
-10,874
$4.00
-43,496
1
$138.71M
2024-01-09
2024-01-10
VALAMEHR BAHRAM
Chief R&D Officer
S - Sale
Common Stock
-11,271
$4.00
-45,084
1
$138.71M
2024-01-09
2024-01-10
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-14,391
$4.00
-57,564
1
$138.71M
2024-01-02
2024-01-03
DULAC EDWARD III
Chief Financial Officer
S - Sale
Common Stock
-5,182
$4.00
-20,728
1
$138.71M
2023-12-26
2023-12-28
REDMILE GROUP, LLC
J - Other
Common Stock
1.66M
$4.00
6.62M
1
$138.71M
2023-12-26
2023-12-28
REDMILE GROUP, LLC
J - Other
Common Stock
-1.66M
$4.00
-6.62M
1
$138.71M
2023-12-26
2023-12-28
REDMILE GROUP, LLC
P - Purchase
Common Stock
44,630
$4.00
179K
1
$138.71M
2023-12-18
2023-12-19
DULAC EDWARD III
Chief Financial Officer
S - Sale
Common Stock
-1,585
$4.00
-6,340
1
$138.71M
2023-11-09
2023-11-13
TAHL CINDY
General Counsel and Secretary
S - Sale
Common Stock
-24,363
$2.00
-48,726
1
$138.71M
2023-08-18
2023-08-21
DULAC EDWARD III
Chief Financial Officer
S - Sale
Common Stock
-4,718
$3.00
-14,154
1
$138.71M
2023-08-04
2023-08-07
XU YUAN
S - Sale
Common Stock
-632
$4.00
-2,528
1
$138.71M
2023-07-05
2023-07-06
DULAC EDWARD III
Chief Financial Officer
S - Sale
Common Stock
-5,182
$5.00
-25,910
1
$138.71M
2023-07-05
2023-07-06
POWL BRIAN
Chief Commercial Officer
S - Sale
Common Stock
-3,854
$5.00
-19,270
1
$138.71M
2023-06-14
2023-06-15
XU YUAN
S - Sale
Common Stock
-3,460
$6.00
-20,760
1
$138.71M
2023-06-06
2023-06-08
REDMILE GROUP, LLC
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2023-06-06
2023-06-08
LEE MICHAEL STEWART
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2023-06-06
2023-06-07
AGARWAL SHEFALI
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2023-06-06
2023-06-07
COUGHLIN TIMOTHY
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2023-06-06
2023-06-07
EPSTEIN ROBERT
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2023-06-06
2023-06-07
HERSHBERG ROBERT
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2023-06-06
2023-06-07
JOOSS KARIN
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2023-06-06
2023-06-07
MENDLEIN JOHN
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2023-06-06
2023-06-07
RASTETTER WILLIAM
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2023-06-06
2023-06-07
XU YUAN
A - Grant
Stock Option (Right to Buy)
40,000
$0.00
1
$138.71M
2023-04-21
2023-04-21
REDMILE GROUP, LLC
P - Purchase
Common Stock
257K
$6.00
1.54M
1
$138.71M
2023-04-20
2023-04-21
REDMILE GROUP, LLC
P - Purchase
Common Stock
20,000
$6.00
120K
1
$138.71M
2023-04-18
2023-04-19
CHU YU-WAYE
Chief Medical Officer
S - Sale
Common Stock
-2,532
$7.00
-17,724
2
$138.71M
2023-04-14
2023-04-17
REDMILE GROUP, LLC
S - Sale
Common Stock
-302K
$6.00
-1.81M
1
$138.71M
2023-04-14
2023-04-17
REDMILE GROUP, LLC
J - Other
Common Stock
-5.49M
$6.00
-33M
1
$138.71M
2023-04-14
2023-04-17
REDMILE GROUP, LLC
P - Purchase
Common Stock
25,700
$6.00
154K
1
$138.71M
2023-04-14
2023-04-17
REDMILE GROUP, LLC
J - Other
Cash-settled Swaps
550K
$6.00
3.30M
1
$138.71M
2023-04-14
2023-04-17
REDMILE GROUP, LLC
J - Other
Class A Convertible Preferred Stock
45,752
$29.00
1.33M
1
$138.71M
2023-04-14
2023-04-17
REDMILE GROUP, LLC
J - Other
Pre-Funded Warrants to Purchase Common Stock
54,960
$6.00
330K
1
$138.71M
2023-04-14
2023-04-17
REDMILE GROUP, LLC
J - Other
Cash-settled Swaps
-550K
$6.00
-3.30M
1
$138.71M
2023-04-14
2023-04-17
REDMILE GROUP, LLC
J - Other
Class A Convertible Preferred Stock
-45,752
$29.00
-1.33M
1
$138.71M
2023-04-14
2023-04-17
REDMILE GROUP, LLC
J - Other
Pre-Funded Warrants to Purchase Common Stock
-54,960
$6.00
-330K
1
$138.71M
2023-04-14
2023-04-17
REDMILE GROUP, LLC
J - Other
Common Stock
5.49M
$6.00
33M
1
$138.71M
2023-04-13
2023-04-17
REDMILE GROUP, LLC
C - Conversion
Common Stock
167K
1
$138.71M
2023-04-13
2023-04-17
REDMILE GROUP, LLC
C - Conversion
Class A Convertible Preferred Stock
-33,441
1
$138.71M
2023-04-14
2023-04-14
REDMILE CAPITAL OFFSHORE FUND (ERISA), LTD.
S - Sale
-135K
$6.00
-811K
1
$138.71M
2023-02-06
2023-02-07
POWL BRIAN
Chief Commercial Officer
A - Grant
Stock Option (Right to Buy)
425K
$0.00
1
$138.71M
2023-02-06
2023-02-07
TAHL CINDY
General Counsel and Secretary
A - Grant
Stock Option (Right to Buy)
425K
$0.00
1
$138.71M
2023-02-06
2023-02-07
VALAMEHR BAHRAM
Chief R&D Officer
A - Grant
Stock Option (Right to Buy)
450K
$0.00
1
$138.71M
2023-02-06
2023-02-07
CHU YU-WAYE
Chief Medical Officer
A - Grant
Stock Option (Right to Buy)
425K
$0.00
1
$138.71M
2023-02-06
2023-02-07
WOLCHKO SCOTT
President and CEO
A - Grant
Stock Option (Right to Buy)
500K
$0.00
1
$138.71M
2023-02-06
2023-02-07
DULAC EDWARD III
Chief Financial Officer
A - Grant
Stock Option (Right to Buy)
425K
$0.00
1
$138.71M
2023-01-19
2023-01-20
MENDLEIN JOHN
M - Exercise
Stock Option (Right to Buy)
28,461
$0.00
1
$138.71M
2023-01-19
2023-01-20
MENDLEIN JOHN
M - Exercise
Common Stock
28,461
$1.00
28,461
1
$138.71M
2023-01-13
2023-01-13
MENDLEIN JOHN
P - Purchase
Common Stock
36,631
$5.00
183K
1
$138.71M
2023-01-12
2023-01-13
VALAMEHR BAHRAM
Chief R&D Officer
M - Exercise
Stock Option (Right to Buy)
423
$0.00
1
$138.71M
2023-01-12
2023-01-13
VALAMEHR BAHRAM
Chief R&D Officer
M - Exercise
Common Stock
423
$1.00
423
1
$138.71M
2023-01-11
2023-01-13
MENDLEIN JOHN
P - Purchase
Common Stock
88,048
$6.00
528K
1
$138.71M
2023-01-10
2023-01-11
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-45,907
$5.00
-230K
1
$138.71M
2023-01-10
2023-01-11
CHU YU-WAYE
Chief Medical Officer
S - Sale
Common Stock
-7,825
$5.00
-39,125
1
$138.71M
2023-01-10
2023-01-11
DULAC EDWARD III
Chief Financial Officer
S - Sale
Common Stock
-7,331
$5.00
-36,655
1
$138.71M
2023-01-10
2023-01-11
PLAVSIC MARK
Chief Technical Officer
S - Sale
Common Stock
-3,418
$5.00
-17,090
1
$138.71M
2023-01-10
2023-01-11
TAHL CINDY
General Counsel and Secretary
S - Sale
Common Stock
-11,553
$5.00
-57,765
1
$138.71M
2023-01-10
2023-01-11
VALAMEHR BAHRAM
Chief R&D Officer
S - Sale
Common Stock
-10,917
$5.00
-54,585
1
$138.71M
2022-08-18
2022-08-19
DULAC EDWARD III
Chief Financial Officer
S - Sale
Common Stock
-5,135
$30.00
-154K
2
$138.71M
2022-07-22
2022-07-25
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (Right to Buy)
-6,246
$0.00
1
$138.71M
2022-07-22
2022-07-25
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
6,246
$3.00
18,738
1
$138.71M
2022-07-22
2022-07-25
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-6,246
$32.00
-200K
3
$138.71M
2022-07-21
2022-07-25
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-30,000
$33.00
-990K
2
$138.71M
2022-07-21
2022-07-25
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
30,000
$3.00
90,000
1
$138.71M
2022-07-21
2022-07-25
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (Right to Buy)
-30,000
$0.00
1
$138.71M
2022-07-07
2022-07-08
VALAMEHR BAHRAM
Chief R&D Officer
M - Exercise
Common Stock
17,158
$3.00
51,474
1
$138.71M
2022-07-07
2022-07-08
VALAMEHR BAHRAM
Chief R&D Officer
M - Exercise
Stock Option (Right to Buy)
-17,158
$3.00
-51,474
1
$138.71M
2022-07-07
2022-07-08
VALAMEHR BAHRAM
Chief R&D Officer
S - Sale
Common Stock
-17,158
$30.00
-515K
1
$138.71M
2022-07-06
2022-07-07
VALAMEHR BAHRAM
Chief R&D Officer
M - Exercise
Stock Option (Right to Buy)
-7,842
$3.00
-23,526
2
$138.71M
2022-07-06
2022-07-07
VALAMEHR BAHRAM
Chief R&D Officer
M - Exercise
Common Stock
7,842
$3.00
23,526
2
$138.71M
2022-07-06
2022-07-07
VALAMEHR BAHRAM
Chief R&D Officer
S - Sale
Common Stock
-7,842
$30.00
-235K
1
$138.71M
2022-07-05
2022-07-06
PLAVSIC MARK
Chief Technical Officer
S - Sale
Common Stock
-3,719
$25.00
-92,975
1
$138.71M
2022-06-27
2022-06-29
POWL BRIAN
Chief Commercial Officer
A - Grant
Stock Option (Right to Buy)
70,000
$0.00
1
$138.71M
2022-06-27
2022-06-29
POWL BRIAN
Chief Commercial Officer
A - Grant
Common Stock
45,000
$0.00
1
$138.71M
2022-06-09
2022-06-13
EPSTEIN ROBERT
A - Grant
Stock Option (Right to Buy)
11,893
$0.00
1
$138.71M
2022-06-09
2022-06-13
AGARWAL SHEFALI
A - Grant
Stock Option (Right to Buy)
11,893
$0.00
1
$138.71M
2022-06-09
2022-06-13
AGARWAL SHEFALI
A - Grant
Common Stock
8,650
$0.00
1
$138.71M
2022-06-09
2022-06-13
COUGHLIN TIMOTHY
A - Grant
Stock Option (Right to Buy)
11,893
$0.00
1
$138.71M
2022-06-09
2022-06-13
COUGHLIN TIMOTHY
A - Grant
Common Stock
8,650
$0.00
1
$138.71M
2022-06-09
2022-06-13
EPSTEIN ROBERT
A - Grant
Common Stock
8,650
$0.00
1
$138.71M
2022-06-09
2022-06-13
HERSHBERG ROBERT
A - Grant
Stock Option (Right to Buy)
11,893
$0.00
1
$138.71M
2022-06-09
2022-06-13
HERSHBERG ROBERT
A - Grant
Common Stock
8,650
$0.00
1
$138.71M
2022-06-09
2022-06-13
JOOSS KARIN
A - Grant
Stock Option (Right to Buy)
11,893
$0.00
1
$138.71M
2022-06-09
2022-06-13
JOOSS KARIN
A - Grant
Common Stock
8,650
$0.00
1
$138.71M
2022-06-09
2022-06-13
LEE MICHAEL STEWART
A - Grant
Stock Option (Right to Buy)
11,893
$0.00
1
$138.71M
2022-06-09
2022-06-13
LEE MICHAEL STEWART
A - Grant
Common Stock
8,650
$0.00
1
$138.71M
2022-06-09
2022-06-13
MENDLEIN JOHN
A - Grant
Stock Option (Right to Buy)
11,893
$0.00
1
$138.71M
2022-06-09
2022-06-13
MENDLEIN JOHN
A - Grant
Common Stock
8,650
$0.00
1
$138.71M
2022-06-09
2022-06-13
RASTETTER WILLIAM
A - Grant
Stock Option (Right to Buy)
11,893
$0.00
1
$138.71M
2022-06-09
2022-06-13
RASTETTER WILLIAM
A - Grant
Common Stock
8,650
$0.00
1
$138.71M
2022-06-09
2022-06-13
REDMILE GROUP, LLC
A - Grant
Stock Option (Right to Buy)
11,893
$0.00
1
$138.71M
2022-06-09
2022-06-13
REDMILE GROUP, LLC
A - Grant
Common Stock
8,650
$0.00
1
$138.71M
2022-06-09
2022-06-13
XU YUAN
A - Grant
Stock Option (Right to Buy)
11,893
$0.00
1
$138.71M
2022-06-09
2022-06-13
XU YUAN
A - Grant
Common Stock
8,650
$0.00
1
$138.71M
2022-06-07
2022-06-08
AGARWAL SHEFALI
S - Sale
Common Stock
-841
$22.00
-18,502
1
$138.71M
2022-06-03
2022-06-06
AGARWAL SHEFALI
S - Sale
Common Stock
-807
$23.00
-18,561
1
$138.71M
2022-06-03
2022-06-06
COUGHLIN TIMOTHY
S - Sale
Common Stock
-1,439
$23.00
-33,097
1
$138.71M
2022-06-03
2022-06-06
HERSHBERG ROBERT
S - Sale
Common Stock
-672
$23.00
-15,456
1
$138.71M
2022-06-03
2022-06-06
JOOSS KARIN
S - Sale
Common Stock
-1,483
$23.00
-34,109
1
$138.71M
2022-06-03
2022-06-06
MENDLEIN JOHN
S - Sale
Common Stock
-1,364
$23.00
-31,372
1
$138.71M
2022-06-01
2022-06-02
TAHL CINDY
General Counsel and Secretary
M - Exercise
Stock Option (Right to Buy)
-25,000
$0.00
1
$138.71M
2022-06-01
2022-06-02
TAHL CINDY
General Counsel and Secretary
M - Exercise
Common Stock
25,000
$7.00
175K
1
$138.71M
2022-06-01
2022-06-02
TAHL CINDY
General Counsel and Secretary
S - Sale
Common Stock
-25,000
$23.00
-575K
1
$138.71M
2022-04-22
2022-04-25
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (Right to Buy)
-10,000
$3.00
-30,000
1
$138.71M
2022-04-22
2022-04-25
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-10,000
$35.00
-350K
2
$138.71M
2022-04-22
2022-04-25
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
10,000
$3.00
30,000
1
$138.71M
2022-04-21
2022-04-25
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-30,000
$35.00
-1.05M
4
$138.71M
2022-04-21
2022-04-25
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (Right to Buy)
-30,000
$3.00
-90,000
1
$138.71M
2022-04-21
2022-04-25
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
30,000
$3.00
90,000
1
$138.71M
2022-04-19
2022-04-21
CHU YU-WAYE
Chief Medical Officer
S - Sale
Common Stock
-4,062
$35.00
-142K
1
$138.71M
2022-04-01
2022-04-04
TAHL CINDY
General Counsel and Secretary
M - Exercise
Stock Option (Right to Buy)
-25,000
$0.00
2
$138.71M
2022-04-01
2022-04-04
TAHL CINDY
General Counsel and Secretary
M - Exercise
Common Stock
25,000
$5.00
125K
2
$138.71M
2022-04-01
2022-04-04
TAHL CINDY
General Counsel and Secretary
S - Sale
Common Stock
-25,000
$39.00
-975K
1
$138.71M
2022-03-14
2022-03-15
VALAMEHR BAHRAM
Chief R&D Officer
M - Exercise
Stock Option (Right to Buy)
-25,000
$0.00
1
$138.71M
2022-03-14
2022-03-15
VALAMEHR BAHRAM
Chief R&D Officer
M - Exercise
Common Stock
25,000
$3.00
75,000
1
$138.71M
2022-03-14
2022-03-15
VALAMEHR BAHRAM
Chief R&D Officer
S - Sale
Common Stock
-25,000
$31.00
-775K
5
$138.71M
2022-03-10
2022-03-11
MENDLEIN JOHN
M - Exercise
Common Stock
31,562
$2.00
63,124
1
$138.71M
2022-03-10
2022-03-11
MENDLEIN JOHN
M - Exercise
Stock Option (Right to Buy)
-31,562
$0.00
1
$138.71M
2022-03-10
2022-03-11
MENDLEIN JOHN
S - Sale
Common Stock
-31,562
$35.00
-1.10M
2
$138.71M
2022-01-21
2022-02-04
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (Right to Buy)
-10,000
$0.00
1
$138.71M
2022-01-20
2022-02-04
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
30,000
$3.00
90,000
1
$138.71M
2022-01-20
2022-02-04
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (Right to Buy)
-30,000
$0.00
1
$138.71M
2022-01-25
2022-01-27
DULAC EDWARD III
Chief Financial Officer
A - Grant
Stock Option (Right to Buy)
53,058
$0.00
1
$138.71M
2022-01-25
2022-01-27
DULAC EDWARD III
Chief Financial Officer
A - Grant
Common Stock
33,302
$0.00
1
$138.71M
2022-01-25
2022-01-27
PLAVSIC MARK
Chief Technical Officer
A - Grant
Stock Option (Right to Buy)
53,058
$0.00
1
$138.71M
2022-01-25
2022-01-27
PLAVSIC MARK
Chief Technical Officer
A - Grant
Common Stock
33,302
$0.00
1
$138.71M
2022-01-25
2022-01-27
TAHL CINDY
General Counsel and Secretary
A - Grant
Stock Option (Right to Buy)
53,058
$0.00
1
$138.71M
2022-01-25
2022-01-27
CHU YU-WAYE
Chief Medical Officer
A - Grant
Stock Option (Right to Buy)
53,058
$0.00
1
$138.71M
2022-01-25
2022-01-27
CHU YU-WAYE
Chief Medical Officer
A - Grant
Common Stock
33,302
$0.00
1
$138.71M
2022-01-25
2022-01-27
TAHL CINDY
General Counsel and Secretary
A - Grant
Common Stock
33,302
$0.00
1
$138.71M
2022-01-25
2022-01-27
VALAMEHR BAHRAM
Chief Research & Development O...
A - Grant
Stock Option (Right to Buy)
53,058
$0.00
1
$138.71M
2022-01-25
2022-01-27
VALAMEHR BAHRAM
Chief Research & Development O...
A - Grant
Common Stock
33,302
$0.00
1
$138.71M
2022-01-25
2022-01-27
WOLCHKO SCOTT
President and CEO
A - Grant
Stock Option (Right to Buy)
289K
$0.00
1
$138.71M
2021-07-01
2022-01-27
TAHL CINDY
General Counsel and Secretary
M - Exercise
Stock Option (Right to Buy)
-15,383
$0.00
1
$138.71M
2022-01-21
2022-01-24
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-10,000
$38.00
-380K
1
$138.71M
2022-01-21
2022-01-24
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (Right to Buy)
-10,000
$3.00
-30,000
1
$138.71M
2022-01-21
2022-01-24
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
10,000
$3.00
30,000
1
$138.71M
2022-01-20
2022-01-24
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (Right to Buy)
-30,000
$3.00
-90,000
1
$138.71M
2022-01-20
2022-01-24
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
30,000
$3.00
90,000
1
$138.71M
2022-01-20
2022-01-24
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-30,000
$40.00
-1.20M
1
$138.71M
2022-01-11
2022-01-13
CHU YU-WAYE
Senior VP Clinical Development
S - Sale
Common Stock
-3,965
$49.00
-194K
2
$138.71M
2022-01-11
2022-01-13
DULAC EDWARD III
Chief Financial Officer
S - Sale
Common Stock
-1,770
$48.00
-84,960
2
$138.71M
2022-01-11
2022-01-13
TAHL CINDY
General Counsel and Secretary
S - Sale
Common Stock
-5,419
$49.00
-266K
2
$138.71M
2022-01-11
2022-01-13
VALAMEHR BAHRAM
Chief R&D Officer
S - Sale
Common Stock
-4,570
$49.00
-224K
2
$138.71M
2022-01-11
2022-01-13
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-14,566
$49.00
-714K
2
$138.71M
2022-01-10
2022-01-12
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-34,156
$47.00
-1.61M
3
$138.71M
2022-01-10
2022-01-12
TAHL CINDY
General Counsel and Secretary
S - Sale
Common Stock
-7,738
$46.00
-356K
2
$138.71M
2022-01-10
2022-01-12
VALAMEHR BAHRAM
Chief R&D Officer
S - Sale
Common Stock
-5,596
$46.00
-257K
2
$138.71M
2022-01-03
2022-01-04
TAHL CINDY
General Counsel and Secretary
M - Exercise
Stock Option (Right to Buy)
-50,000
$0.00
1
$138.71M
2022-01-03
2022-01-04
TAHL CINDY
General Counsel and Secretary
M - Exercise
Common Stock
50,000
$7.00
350K
1
$138.71M
2022-01-03
2022-01-04
TAHL CINDY
General Counsel and Secretary
S - Sale
Common Stock
-50,000
$59.00
-2.95M
4
$138.71M
2021-12-20
2021-12-21
DULAC EDWARD III
Chief Financial Officer
M - Exercise
Stock Option (Right to Buy)
-14,437
$0.00
1
$138.71M
2021-12-20
2021-12-21
DULAC EDWARD III
Chief Financial Officer
M - Exercise
Common Stock
14,437
$36.00
520K
1
$138.71M
2021-12-20
2021-12-21
DULAC EDWARD III
Chief Financial Officer
S - Sale
Common Stock
-15,977
$60.00
-959K
1
$138.71M
2021-12-13
2021-12-14
VALAMEHR BAHRAM
Chief R&D Officer
M - Exercise
Stock Option (Right to Buy)
25,000
$0.00
1
$138.71M
2021-12-13
2021-12-14
VALAMEHR BAHRAM
Chief R&D Officer
M - Exercise
Common Stock
25,000
$3.00
75,000
1
$138.71M
2021-12-13
2021-12-14
VALAMEHR BAHRAM
Chief R&D Officer
S - Sale
Common Stock
-25,000
$48.00
-1.20M
5
$138.71M
2021-12-10
2021-12-13
CHU YU-WAYE
Senior VP Clinical Development
M - Exercise
Stock Option (Right to Buy)
-7,500
$0.00
1
$138.71M
2021-12-10
2021-12-13
CHU YU-WAYE
Senior VP Clinical Development
M - Exercise
Common Stock
7,500
$16.00
120K
1
$138.71M
2021-12-10
2021-12-13
CHU YU-WAYE
Senior VP Clinical Development
S - Sale
Common Stock
-7,500
$51.00
-383K
7
$138.71M
2021-11-19
2021-11-22
PLAVSIC MARK
Chief Technical Officer
A - Grant
Common Stock
59,540
$0.00
1
$138.71M
2021-11-19
2021-11-22
VALAMEHR BAHRAM
Chief R&D Officer
A - Grant
Common Stock
60,958
$0.00
1
$138.71M
2021-11-19
2021-11-22
WOLCHKO SCOTT
President and CEO
A - Grant
Common Stock
86,475
$0.00
1
$138.71M
2021-11-19
2021-11-22
CHU YU-WAYE
Senior VP Clinical Development
A - Grant
Common Stock
60,958
$0.00
1
$138.71M
2021-11-19
2021-11-22
DULAC EDWARD III
Chief Financial Officer
A - Grant
Common Stock
59,540
$0.00
1
$138.71M
2021-11-19
2021-11-22
TAHL CINDY
General Counsel and Secretary
A - Grant
Common Stock
60,958
$0.00
1
$138.71M
2021-11-18
2021-11-22
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-20,000
$54.00
-1.08M
1
$138.71M
2021-11-18
2021-11-22
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (right to buy)
-20,000
$0.00
1
$138.71M
2021-11-18
2021-11-22
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
20,000
$3.00
60,000
1
$138.71M
2021-10-22
2021-10-25
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (Right to Buy)
-30,000
$0.00
3
$138.71M
2021-10-22
2021-10-25
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
30,000
$3.00
90,000
3
$138.71M
2021-10-22
2021-10-25
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-30,000
$59.00
-1.77M
1
$138.71M
2021-10-21
2021-10-25
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
30,000
$3.00
90,000
1
$138.71M
2021-10-21
2021-10-25
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (Right to Buy)
-30,000
$0.00
1
$138.71M
2021-10-21
2021-10-25
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-30,000
$60.00
-1.80M
2
$138.71M
2021-10-01
2021-10-04
TAHL CINDY
General Counsel and Secretary
M - Exercise
Stock Option (Right to Buy)
-50,000
$0.00
1
$138.71M
2021-10-01
2021-10-04
TAHL CINDY
General Counsel and Secretary
M - Exercise
Common Stock
50,000
$7.00
350K
1
$138.71M
2021-10-01
2021-10-04
TAHL CINDY
General Counsel and Secretary
S - Sale
Common Stock
-50,000
$59.00
-2.95M
3
$138.71M
2021-09-28
2021-09-30
DULAC EDWARD III
Chief Financial Officer
M - Exercise
Common Stock
17,325
$36.00
624K
1
$138.71M
2021-09-28
2021-09-30
DULAC EDWARD III
Chief Financial Officer
M - Exercise
Stock Option (Right to Buy)
-17,325
$0.00
1
$138.71M
2021-09-28
2021-09-30
DULAC EDWARD III
Chief Financial Officer
S - Sale
Common Stock
-19,460
$63.00
-1.23M
1
$138.71M
2021-09-13
2021-09-14
VALAMEHR BAHRAM
Chief Development Officer
M - Exercise
Stock Option (Right to Buy)
-25,000
$0.00
1
$138.71M
2021-09-13
2021-09-14
VALAMEHR BAHRAM
Chief Development Officer
M - Exercise
Common Stock
25,000
$3.00
75,000
1
$138.71M
2021-09-13
2021-09-14
VALAMEHR BAHRAM
Chief Development Officer
S - Sale
Common Stock
-25,000
$66.00
-1.65M
3
$138.71M
2021-08-19
2021-08-20
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (Right to Buy)
-20,000
$0.00
1
$138.71M
2021-08-19
2021-08-20
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
20,000
$5.00
100K
1
$138.71M
2021-08-19
2021-08-20
DULAC EDWARD III
Chief Financial Officer
S - Sale
Common Stock
-3,474
$88.00
-306K
3
$138.71M
2021-08-19
2021-08-20
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-20,000
$88.00
-1.76M
1
$138.71M
2021-08-03
2021-08-05
XU YUAN
A - Grant
Stock Option (Right to Buy)
7,501
$0.00
1
$138.71M
2021-08-03
2021-08-05
XU YUAN
A - Grant
Common Stock
4,744
$0.00
1
$138.71M
2021-07-23
2021-07-26
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (Right to Buy)
-30,000
$0.00
2
$138.71M
2021-07-23
2021-07-26
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
30,000
$4.00
120K
2
$138.71M
2021-07-23
2021-07-26
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-30,000
$85.00
-2.55M
1
$138.71M
2021-07-22
2021-07-26
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (Right to Buy)
-30,000
$0.00
1
$138.71M
2021-07-22
2021-07-26
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-30,000
$86.00
-2.58M
3
$138.71M
2021-07-22
2021-07-26
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
30,000
$3.00
90,000
1
$138.71M
2021-07-01
2021-07-02
TAHL CINDY
General Counsel and Secretary
S - Sale
Common Stock
-55,534
$85.00
-4.72M
11
$138.71M
2021-07-01
2021-07-02
TAHL CINDY
General Counsel and Secretary
M - Exercise
Stock Option (Right to Buy)
-55,534
$0.00
4
$138.71M
2021-07-01
2021-07-02
TAHL CINDY
General Counsel and Secretary
M - Exercise
Common Stock
55,534
$6.00
333K
4
$138.71M
2021-06-14
2021-06-22
PLAVSIC MARK
Chief Technical Officer
A - Grant
Stock Option (Right to Buy)
18,500
$0.00
1
$138.71M
2021-06-14
2021-06-22
PLAVSIC MARK
Chief Technical Officer
A - Grant
Common Stock
38,000
$0.00
1
$138.71M
2021-06-14
2021-06-16
VALAMEHR BAHRAM
Chief Development Officer
M - Exercise
Common Stock
25,000
$3.00
75,000
2
$138.71M
2021-06-14
2021-06-16
VALAMEHR BAHRAM
Chief Development Officer
M - Exercise
Stock Option (Right to Buy)
-25,000
$0.00
2
$138.71M
2021-06-14
2021-06-16
VALAMEHR BAHRAM
Chief Development Officer
S - Sale
Common Stock
-25,000
$89.00
-2.23M
3
$138.71M
2021-06-02
2021-06-04
LEE MICHAEL STEWART
A - Grant
Common Stock
2,681
$0.00
1
$138.71M
2021-06-02
2021-06-04
MENDLEIN JOHN
A - Grant
Stock Option (Right to Buy)
4,334
$0.00
1
$138.71M
2021-06-02
2021-06-04
MENDLEIN JOHN
A - Grant
Common Stock
2,681
$0.00
1
$138.71M
2021-06-02
2021-06-04
RASTETTER WILLIAM
A - Grant
Stock Option (Right to Buy)
4,334
$0.00
1
$138.71M
2021-06-02
2021-06-04
RASTETTER WILLIAM
A - Grant
Common Stock
2,681
$0.00
1
$138.71M
2021-06-02
2021-06-04
REDMILE GROUP, LLC
A - Grant
Stock Option (Right to Buy)
4,334
$0.00
1
$138.71M
2021-06-02
2021-06-04
REDMILE GROUP, LLC
A - Grant
Common Stock
2,681
$0.00
1
$138.71M
2021-06-02
2021-06-04
HERSHBERG ROBERT
A - Grant
Common Stock
2,681
$0.00
1
$138.71M
2021-06-02
2021-06-04
AGARWAL SHEFALI
A - Grant
Stock Option (Right to Buy)
4,334
$0.00
1
$138.71M
2021-06-02
2021-06-04
AGARWAL SHEFALI
A - Grant
Common Stock
2,681
$0.00
1
$138.71M
2021-06-02
2021-06-04
COUGHLIN TIMOTHY
A - Grant
Stock Option (Right to Buy)
4,334
$0.00
1
$138.71M
2021-06-02
2021-06-04
COUGHLIN TIMOTHY
A - Grant
Common Stock
2,681
$0.00
1
$138.71M
2021-06-02
2021-06-04
EPSTEIN ROBERT
A - Grant
Stock Option (Right to Buy)
4,334
$0.00
1
$138.71M
2021-06-02
2021-06-04
EPSTEIN ROBERT
A - Grant
Common Stock
2,681
$0.00
1
$138.71M
2021-06-02
2021-06-04
HERSHBERG ROBERT
A - Grant
Stock Option (Right to Buy)
4,334
$0.00
1
$138.71M
2021-06-02
2021-06-04
JOOSS KARIN
A - Grant
Stock Option (Right to Buy)
4,334
$0.00
1
$138.71M
2021-06-02
2021-06-04
JOOSS KARIN
A - Grant
Common Stock
2,681
$0.00
1
$138.71M
2021-06-02
2021-06-04
LEE MICHAEL STEWART
A - Grant
Stock Option (Right to Buy)
4,334
$0.00
1
$138.71M
2021-05-20
2021-05-24
WOLCHKO SCOTT
President and CEO
M - Exercise
Common stock
20,000
$5.00
100K
1
$138.71M
2021-05-20
2021-05-24
WOLCHKO SCOTT
President and CEO
S - Sale
Common stock
-20,000
$77.00
-1.54M
1
$138.71M
2021-05-20
2021-05-24
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (right to buy)
-20,000
1
$138.71M
2021-04-23
2021-04-26
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (right to buy)
-30,000
3
$138.71M
2021-04-23
2021-04-26
WOLCHKO SCOTT
President and CEO
M - Exercise
Common stock
30,000
$5.00
150K
3
$138.71M
2021-04-23
2021-04-26
WOLCHKO SCOTT
President and CEO
S - Sale
Common stock
-30,000
$85.00
-2.55M
1
$138.71M
2021-04-22
2021-04-26
WOLCHKO SCOTT
President and CEO
S - Sale
Common stock
-30,000
$86.00
-2.58M
1
$138.71M
2021-04-22
2021-04-26
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (right to buy)
-30,000
1
$138.71M
2021-04-22
2021-04-26
WOLCHKO SCOTT
President and CEO
M - Exercise
Common stock
30,000
$3.00
90,000
1
$138.71M
2021-04-16
2021-04-20
CHU YU-WAYE
Senior VP Clinical Development
S - Sale
Common stock
-3,275
$83.00
-272K
3
$138.71M
2021-04-01
2021-04-02
TAHL CINDY
General Counsel and Secretary
M - Exercise
Stock Option Right to Buy
-1,851
$0.00
1
$138.71M
2021-04-01
2021-04-02
TAHL CINDY
General Counsel and Secretary
S - Sale
Common Stock
-30,000
$84.00
-2.52M
8
$138.71M
2021-04-01
2021-04-02
TAHL CINDY
General Counsel and Secretary
M - Exercise
Stock Option (Right to Buy)
-28,149
$0.00
1
$138.71M
2021-04-01
2021-04-02
TAHL CINDY
General Counsel and Secretary
M - Exercise
Common Stock
30,000
$3.00
90,000
2
$138.71M
2020-03-30
2021-04-02
RASTETTER WILLIAM
G - Gift
Common Stock
28,461
$0.00
1
$138.71M
2020-03-30
2021-04-02
RASTETTER WILLIAM
G - Gift
Common Stock
-28,461
$0.00
1
$138.71M
2021-03-15
2021-03-16
VALAMEHR BAHRAM
Chief Development Officer
M - Exercise
Stock Option (Right to Buy)
-25,000
$0.00
1
$138.71M
2021-03-15
2021-03-16
VALAMEHR BAHRAM
Chief Development Officer
M - Exercise
Common Stock
-25,000
$3.00
-75,000
1
$138.71M
2021-03-15
2021-03-16
VALAMEHR BAHRAM
Chief Development Officer
S - Sale
Common Stock
-25,000
$92.00
-2.30M
5
$138.71M
2021-03-08
2021-03-09
SHOEMAKER DANIEL
Chief Scientific Officer
S - Sale
Common stock
-25,000
$82.00
-2.05M
8
$138.71M
2021-02-18
2021-02-19
WOLCHKO SCOTT
President and CEO
S - Sale
Common stock
-20,000
$102.00
-2.04M
5
$138.71M
2021-02-18
2021-02-19
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (right to buy)
-20,000
1
$138.71M
2021-02-18
2021-02-19
WOLCHKO SCOTT
President and CEO
M - Exercise
Common stock
20,000
$7.00
140K
1
$138.71M
2021-01-22
2021-01-22
WOLCHKO SCOTT
President and CEO
S - Sale
Common stock
-30,000
$98.00
-2.94M
4
$138.71M
2021-01-22
2021-01-22
WOLCHKO SCOTT
President and CEO
M - Exercise
Common stock
30,000
$5.00
150K
2
$138.71M
2021-01-22
2021-01-22
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (right to buy)
-30,000
2
$138.71M
2021-01-21
2021-01-22
WOLCHKO SCOTT
President and CEO
S - Sale
Common stock
-30,000
$103.00
-3.09M
8
$138.71M
2021-01-21
2021-01-22
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (right to buy)
-30,000
1
$138.71M
2021-01-21
2021-01-22
WOLCHKO SCOTT
President and CEO
M - Exercise
Common stock
30,000
$3.00
90,000
1
$138.71M
2021-01-20
2021-01-22
TAHL CINDY
General Counsel and Secretary
A - Grant
Stock Option (right to buy)
6,851
1
$138.71M
2021-01-20
2021-01-22
DULAC EDWARD III
Chief Financial Officer
A - Grant
Stock Option (right to buy)
6,851
1
$138.71M
2021-01-20
2021-01-22
VALAMEHR BAHRAM
Chief Development Officer
A - Grant
Stock Option (right to buy)
6,851
1
$138.71M
2021-01-20
2021-01-22
VALAMEHR BAHRAM
Chief Development Officer
A - Grant
Common stock
18,013
$0.00
1
$138.71M
2021-01-20
2021-01-22
WOLCHKO SCOTT
President and CEO
A - Grant
Stock Option (right to buy)
16,441
1
$138.71M
2021-01-20
2021-01-22
WOLCHKO SCOTT
President and CEO
A - Grant
Common stock
43,231
$0.00
1
$138.71M
2021-01-20
2021-01-22
DULAC EDWARD III
Chief Financial Officer
A - Grant
Common stock
18,013
$0.00
1
$138.71M
2021-01-20
2021-01-22
SHOEMAKER DANIEL
Chief Scientific Officer
A - Grant
Stock Option (right to buy)
5,481
1
$138.71M
2021-01-20
2021-01-22
SHOEMAKER DANIEL
Chief Scientific Officer
A - Grant
Common stock
14,411
$0.00
1
$138.71M
2021-01-20
2021-01-22
TAHL CINDY
General Counsel and Secretary
A - Grant
Common stock
18,013
$0.00
1
$138.71M
2021-01-19
2021-01-21
TAHL CINDY
General Counsel and Secretary
M - Exercise
Stock Option (right to buy)
-35,000
1
$138.71M
2021-01-19
2021-01-21
TAHL CINDY
General Counsel and Secretary
M - Exercise
Common stock
35,000
$3.00
105K
1
$138.71M
2021-01-19
2021-01-21
TAHL CINDY
General Counsel and Secretary
S - Sale
Common stock
-35,000
$115.00
-4.03M
4
$138.71M
2021-01-11
2021-01-12
WOLCHKO SCOTT
President and CEO
S - Sale
Common stock
-8,587
$111.00
-953K
3
$138.71M
2021-01-11
2021-01-12
VALAMEHR BAHRAM
Chief Development Officer
S - Sale
Common stock
-3,254
$111.00
-361K
3
$138.71M
2021-01-11
2021-01-12
TAHL CINDY
General Counsel and Secretary
S - Sale
Common stock
-3,254
$111.00
-361K
3
$138.71M
2021-01-11
2021-01-12
SHOEMAKER DANIEL
Chief Scientific Officer
S - Sale
Common stock
-3,253
$111.00
-361K
3
$138.71M
2021-01-08
2021-01-12
WOLCHKO SCOTT
President and CEO
S - Sale
Common stock
-60,820
$117.00
-7.12M
4
$138.71M
2021-01-08
2021-01-12
REDMILE GROUP, LLC
P - Purchase
Pre-Funded Warrant to Purchase Common Stock
257K
$85.00
22M
1
$138.71M
2021-01-08
2021-01-12
REDMILE GROUP, LLC
P - Purchase
Common Stock
327K
$86.00
28M
1
$138.71M
2021-01-08
2021-01-12
SHOEMAKER DANIEL
Chief Scientific Officer
S - Sale
Common stock
-6,229
$117.00
-729K
4
$138.71M
2021-01-08
2021-01-12
TAHL CINDY
General Counsel and Secretary
S - Sale
Common stock
-6,229
$117.00
-729K
4
$138.71M
2021-01-08
2021-01-12
VALAMEHR BAHRAM
Chief Development Officer
S - Sale
Common stock
-6,230
$117.00
-729K
4
$138.71M
2020-12-17
2020-12-18
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (right to buy)
-20,000
1
$138.71M
2020-12-17
2020-12-18
WOLCHKO SCOTT
President and CEO
M - Exercise
Common stock
20,000
$7.00
140K
1
$138.71M
2020-12-17
2020-12-18
WOLCHKO SCOTT
President and CEO
S - Sale
Common stock
-20,000
$92.00
-1.84M
4
$138.71M
2020-12-14
2020-12-15
VALAMEHR BAHRAM
Chief Development Officer
M - Exercise
Stock Option (right to buy)
-25,000
1
$138.71M
2020-12-14
2020-12-15
VALAMEHR BAHRAM
Chief Development Officer
M - Exercise
Common stock
25,000
$3.00
75,000
1
$138.71M
2020-12-14
2020-12-15
VALAMEHR BAHRAM
Chief Development Officer
S - Sale
Common stock
-25,000
$98.00
-2.45M
8
$138.71M
2020-11-16
2020-11-16
SHOEMAKER DANIEL
Chief Scientific Officer
S - Sale
Common stock
-25,000
$52.00
-1.30M
3
$138.71M
2020-11-13
2020-11-16
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
10,000
$3.00
30,000
1
$138.71M
2020-11-13
2020-11-16
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (right to buy)
-30,000
3
$138.71M
2020-11-13
2020-11-16
WOLCHKO SCOTT
President and CEO
M - Exercise
Common stock
20,000
$7.00
140K
2
$138.71M
2020-11-13
2020-11-16
WOLCHKO SCOTT
President and CEO
S - Sale
Common stock
-30,000
$51.00
-1.53M
3
$138.71M
2020-11-12
2020-11-16
WOLCHKO SCOTT
President and CEO
M - Exercise
Common stock
30,000
$3.00
90,000
1
$138.71M
2020-11-12
2020-11-16
WOLCHKO SCOTT
President and CEO
S - Sale
Common stock
-30,000
$53.00
-1.59M
4
$138.71M
2020-11-12
2020-11-16
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (right to buy)
-30,000
1
$138.71M
2020-11-05
2020-11-06
TAHL CINDY
General Counsel and Secretary
M - Exercise
Common stock
19,282
$3.00
57,846
2
$138.71M
2020-11-05
2020-11-06
TAHL CINDY
General Counsel and Secretary
S - Sale
Common stock
-19,282
$51.00
-983K
2
$138.71M
2020-11-05
2020-11-06
TAHL CINDY
General Counsel and Secretary
M - Exercise
Stock Option (right to buy)
-19,282
2
$138.71M
2020-11-04
2020-11-06
TAHL CINDY
General Counsel and Secretary
M - Exercise
Common stock
51,519
$3.00
155K
1
$138.71M
2020-11-04
2020-11-06
TAHL CINDY
General Counsel and Secretary
M - Exercise
Stock Option (right to buy)
-51,519
1
$138.71M
2020-11-04
2020-11-06
TAHL CINDY
General Counsel and Secretary
S - Sale
Common stock
-51,519
$50.00
-2.58M
1
$138.71M
2020-10-16
2020-10-20
TAHL CINDY
General Counsel and Secretary
M - Exercise
Stock Option (right to buy)
-29,199
1
$138.71M
2020-10-16
2020-10-20
TAHL CINDY
General Counsel and Secretary
M - Exercise
Common stock
29,199
$3.00
87,597
1
$138.71M
2020-10-16
2020-10-20
TAHL CINDY
General Counsel and Secretary
S - Sale
Common stock
-29,199
$50.00
-1.46M
1
$138.71M
2020-10-01
2020-10-02
TAHL CINDY
General Counsel and Secretary
M - Exercise
Stock Option (right to buy)
-35,000
1
$138.71M
2020-10-01
2020-10-02
TAHL CINDY
General Counsel and Secretary
M - Exercise
Common stock
35,000
$3.00
105K
1
$138.71M
2020-10-01
2020-10-02
TAHL CINDY
General Counsel and Secretary
S - Sale
Common stock
-35,000
$41.00
-1.44M
3
$138.71M
2020-09-14
2020-09-16
VALAMEHR BAHRAM
Chief Development Officer
M - Exercise
Stock Option (right to buy)
-25,000
2
$138.71M
2020-09-14
2020-09-16
VALAMEHR BAHRAM
Chief Development Officer
M - Exercise
Common stock
25,000
$3.00
75,000
2
$138.71M
2020-09-14
2020-09-16
SHOEMAKER DANIEL
Chief Scientific Officer
S - Sale
Common stock
-25,000
$36.00
-900K
3
$138.71M
2020-09-14
2020-09-16
VALAMEHR BAHRAM
Chief Development Officer
S - Sale
Common stock
-25,000
$36.00
-900K
4
$138.71M
2020-08-17
2020-08-19
DULAC EDWARD III
Chief Financial Officer
A - Grant
Stock Option (right to buy)
160K
$0.00
1
$138.71M
2020-08-17
2020-08-19
DULAC EDWARD III
Chief Financial Officer
A - Grant
Common stock
40,000
$0.00
1
$138.71M
2020-06-11
2020-06-17
REDMILE GROUP, LLC
P - Purchase
Common Stock
1.41M
$28.00
40M
1
$138.71M
2020-05-01
2020-05-05
AGARWAL SHEFALI
A - Grant
Stock Option (right to buy)
16,000
1
$138.71M
2020-05-01
2020-05-05
COUGHLIN TIMOTHY
A - Grant
Stock Option (right to buy)
16,000
1
$138.71M
2020-05-01
2020-05-05
EPSTEIN ROBERT
A - Grant
Stock Option (right to buy)
16,000
1
$138.71M
2020-05-01
2020-05-05
HERSHBERG ROBERT
A - Grant
Stock Option (right to buy)
40,000
2
$138.71M
2020-05-01
2020-05-05
JOOSS KARIN
A - Grant
Stock Option (right to buy)
16,000
1
$138.71M
2020-05-01
2020-05-05
LEE MICHAEL STEWART
A - Grant
Stock Option (Right to Buy)
16,000
$0.00
1
$138.71M
2020-05-01
2020-05-05
MENDLEIN JOHN
A - Grant
Stock Option (right to buy)
16,000
1
$138.71M
2020-05-01
2020-05-05
RASTETTER WILLIAM
A - Grant
Stock Option (right to buy)
16,000
1
$138.71M
2020-05-01
2020-05-05
REDMILE GROUP, LLC
A - Grant
Stock Option (Right to Buy)
16,000
$0.00
1
$138.71M
2020-03-30
2020-03-31
RASTETTER WILLIAM
M - Exercise
Stock Option (right to buy)
-28,461
1
$138.71M
2020-03-30
2020-03-31
RASTETTER WILLIAM
M - Exercise
Common stock
28,461
$1.00
28,461
1
$138.71M
2020-02-03
2020-02-04
VALAMEHR BAHRAM
Chief Development Officer
M - Exercise
Stock Option (right to buy)
-1,153
1
$138.71M
2020-02-03
2020-02-04
VALAMEHR BAHRAM
Chief Development Officer
M - Exercise
Common Stock
1,153
$2.00
2,306
1
$138.71M
2020-01-30
2020-02-03
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (right to buy)
-25,000
1
$138.71M
2020-01-30
2020-02-03
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
25,000
$3.00
75,000
1
$138.71M
2020-01-30
2020-02-03
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-25,000
$25.00
-625K
1
$138.71M
2020-01-08
2020-01-10
SHOEMAKER DANIEL
Chief Scientific Officer
A - Grant
Stock Option (right to buy)
90,000
1
$138.71M
2020-01-08
2020-01-10
SHOEMAKER DANIEL
Chief Scientific Officer
A - Grant
Common Stock
25,000
$0.00
1
$138.71M
2020-01-08
2020-01-10
TAHL CINDY
General Counsel and Secretary
A - Grant
Stock Option (right to buy)
90,000
1
$138.71M
2020-01-08
2020-01-10
TAHL CINDY
General Counsel and Secretary
A - Grant
Common Stock
25,000
$0.00
1
$138.71M
2020-01-08
2020-01-10
VALAMEHR BAHRAM
Chief Development Officer
A - Grant
Stock Option (right to buy)
90,000
1
$138.71M
2020-01-08
2020-01-10
VALAMEHR BAHRAM
Chief Development Officer
A - Grant
Common Stock
25,000
$0.00
1
$138.71M
2020-01-08
2020-01-10
WOLCHKO SCOTT
President and CEO
A - Grant
Stock Option (right to buy)
219K
1
$138.71M
2020-01-08
2020-01-10
WOLCHKO SCOTT
President and CEO
A - Grant
Common Stock
66,000
$0.00
1
$138.71M
2020-01-08
2020-01-10
SHOEMAKER DANIEL
Chief Scientific Officer
S - Sale
Common Stock
-5,700
$21.00
-120K
1
$138.71M
2020-01-08
2020-01-10
TAHL CINDY
General Counsel and Secretary
S - Sale
Common Stock
-5,700
$21.00
-120K
1
$138.71M
2020-01-08
2020-01-10
VALAMEHR BAHRAM
Chief Development Officer
S - Sale
Common Stock
-5,700
$21.00
-120K
1
$138.71M
2019-12-30
2020-01-02
SHOEMAKER DANIEL
Chief Scientific Officer
M - Exercise
Stock Option (right to buy)
-25,000
1
$138.71M
2019-12-30
2020-01-02
SHOEMAKER DANIEL
Chief Scientific Officer
M - Exercise
Common Stock
25,000
$3.00
75,000
1
$138.71M
2019-12-30
2020-01-02
SHOEMAKER DANIEL
Chief Scientific Officer
S - Sale
Common Stock
-25,000
$19.00
-475K
2
$138.71M
2019-12-20
2019-12-23
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-25,000
$20.00
-500K
1
$138.71M
2019-12-20
2019-12-23
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (right to buy)
-25,000
1
$138.71M
2019-12-20
2019-12-23
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
25,000
$3.00
75,000
1
$138.71M
2019-12-19
2019-12-23
WOLCHKO SCOTT
President and CEO
M - Exercise
Stock Option (right to buy)
-25,000
1
$138.71M
2019-12-19
2019-12-23
WOLCHKO SCOTT
President and CEO
M - Exercise
Common Stock
25,000
$3.00
75,000
1
$138.71M
2019-12-19
2019-12-23
WOLCHKO SCOTT
President and CEO
S - Sale
Common Stock
-25,000
$20.00
-500K
1
$138.71M